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T-antigen is not bound to the replication origin of the simian virus 40 late transcription complex


T-antigen is not bound to the replication origin of the simian virus 40 late transcription complex



Journal of Molecular Biology 215(1): 53-65



ISSN/ISBN: 0022-2836

PMID: 2168948

DOI: 10.1016/s0022-2836(05)80094-4

Simian virus 40 tumor antigen (T-antigen) plays a central role in determining which gene is transcribed from viral DNA late in infection. Results from several studies have led to a model in which the binding of T-antigen to the viral origin of replication results in repression of transcription from the stronger early gene promoter and stimulation of transcription from the late gene promoter.

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Accession: 018142922

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Related references

T antigen is not bound to the replication origin of the sv 40 late transcription complex. Journal of Molecular Biology 215(1): 53-66, 1990

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