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The application of a sequential procedure with elimination as a method for the screening for metabolic diseases


The application of a sequential procedure with elimination as a method for the screening for metabolic diseases



Biometrics 40(3): 663-673



ISSN/ISBN: 0006-341X

PMID: 6518244

DOI: 10.2307/2530909

A sequential classification procedure with early elimination, for the screening for metabolic diseases, is presented. Asymptotic properties of the procedure are derived in the Appendix and it is shown that the procedure is asymptotically distribution-free under certain assumptions, and asymptotically at least as efficient as a comparable fixed-sample procedure. With the use of data obtained from 36 mentally retarded patients, the procedure was evaluated by means of a bootstrap simulation. The procedure was then applied to this set of data, with satisfactory results and a considerable economy in observations.

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Accession: 018160344

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