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The patch clamp is more useful than anyone had expected


The patch clamp is more useful than anyone had expected



Federation Proceedings 45(12): 2673-2677



ISSN/ISBN: 0014-9446

PMID: 2429870

The patch clamp was developed into its present form by Neher and Sakmann for recording the currents through individual ionic channels in excitable membranes. Recent advances now allow the patch-clamp technique to be used to record from cell-free membrane patches and from entire small cells. The technique has been used extensively for recordings from single channels that have provided new insights into their functioning; it is also being applied to a surprising variety of other physiological problems.

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Accession: 018175222

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