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Toxigenic diarrheas, congenital diarrheas, and cystic fibrosis: disorders of intestinal ion transport



Toxigenic diarrheas, congenital diarrheas, and cystic fibrosis: disorders of intestinal ion transport



Annual Review of Physiology 55: 631-655



The various details provided by physical methods have been integrated into a coherent picture of the cation transport process. The free energy profile describes simultaneously the thermodynamic and kinetic factors that govern conductance. Localization of ion binding sites near each end of the channel by NMR and X-ray crystallographic techniques demonstrates that there is an energy barrier separating the two ends.

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Accession: 018188155

Download citation: RISBibTeXText

PMID: 7682048

DOI: 10.1146/annurev.ph.55.030193.003215


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