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Tumor necrosis, cachexia, shock, and inflammation: a common mediator


Tumor necrosis, cachexia, shock, and inflammation: a common mediator



Annual Review of Biochemistry 57: 505-518



ISSN/ISBN: 0066-4154

PMID: 3052281

DOI: 10.1146/annurev.bi.57.070188.002445

A class of membrane molecules has been identified whose primary translation product includes a COOH-terminal protein sequence that signals attachment of a glycosyl-phosphatidylinositol anchor at a COOH-terminal residue that is newly formed by cleavage of the signaling sequence. This class includes a wide diversity of protein types from eukaryotes at many stages of evolution.

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Accession: 018194358

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