+ Translate
+ Most Popular
Investigations on the organic drift in North Swedish streams
Limitations of Using Microsoft Excel Version 2016 (MS Excel 2016) for Statistical Analysis for Medical Research
Phloem necrosis of coffee in Surinam
Anatomy of Mystus seenghala IV Nervous system
Integrated farming system for gardenland conditions of Coimbatore district - an over view
Tetrapleure (Tetrapleura tetraptera), an unknown African medicinal and spice plant
The origin and phylogenetic significance of the trochophoran larvae 2. evolutionary significance of the larvae of coelomate worms and mollusks
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Enterobacter amnigenus. An unusual human pathogen
Influence of Seriboost foliar application on leaf yield and leaf protein content in mulberry (Morus spp.), in relation to silkworm cocoon production
The identity of the lipstick mold of cultivated mushrooms agaricus bisporus
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
'Pan-sukh' disease of Rice in the Central Provinces
Geological age of the Ptilophyllum flora; a critical reassessment
Study of vitellogenesis in birds; physiological phases & role of folliculin in vitellogenesis
Evaluation of WCT coconut and Komadan coconut
Therapy for acne with saccharomyces boulardii
Evidence for Late Cretaceous N-S dextral shear in the west-central crystalline core, North Cascades, Washington
'Rajeshwari' - a high-yielding white seeded variety of sesame for Andhra Pradesh
Manufacture of Ricotta cheese from whey fortified with skim milk powder using different acidulants
Occurrence of Eutrichophilus mexicanus (Rudow, 1866) and Eutrichophilus lobatus (Ewing, 1936) (Phthiraptera: Trichodectidae) on Sphiggurus villosus (Cuvier, 1825) (Rodentia: Erethizontidae) in Rio de
Factors affecting fruitfulness in durian (Durio zibethinus Murr.). I. Flowering and pollination
Bronchial cuff pressure change caused by left-sided double-lumen endobronchial tube displacement
Some Biological Applications of Organometallic Compounds
The composition of pampas-grass (Cortaderia argentea.)

Tumor necrosis, cachexia, shock, and inflammation: a common mediator

Tumor necrosis, cachexia, shock, and inflammation: a common mediator

Annual Review of Biochemistry 57: 505-518

ISSN/ISBN: 0066-4154

PMID: 3052281

DOI: 10.1146/

A class of membrane molecules has been identified whose primary translation product includes a COOH-terminal protein sequence that signals attachment of a glycosyl-phosphatidylinositol anchor at a COOH-terminal residue that is newly formed by cleavage of the signaling sequence. This class includes a wide diversity of protein types from eukaryotes at many stages of evolution.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 018194358

Download citation: RISBibTeXText

Related references

The common mediator of shock, cachexia, and tumor necrosis. Advances in Immunology 42: 213-231, 1988

Tumor necrosis factor as a mediator of shock, cachexia and inflammation. Blood Purification 11(2): 108-117, 1993

Cachectin/tumor necrosis factor: an endogenous mediator of shock and inflammation. Immunologic Research 5(4): 281-293, 1986

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation. Journal of Experimental Medicine 167(3): 1211-1227, 1988

The regulatory role of tumor necrosis factor tnf in shock cachexia and neoplasia. Proceedings of the American Association for Cancer Research Annual Meeting 31: 497, 1990

Tumor necrosis factor a mediator of inflammation. Messmer, K And F Hammersen (Ed ) Mikrozirkulation in Forschung Und Klinik, Vol 12 Microcirculation And Inflammation: Vessel Wall-Inflammatory Cells-Mediator Interaction; (Progress in Applied Microcirculation, Vol 12 Microcirculation And Inflammation: Vessel Wall-Inflammatory Cells-Mediator Interaction); 6th Bodensee Symposium, Heidelberg, West Germany, June 22-25, 1986 Xv+329p S Karger Ag: Basel, Switzerland; New York, New York, Usa Illus Paper 124-131, 1987

Tumor necrosis factor. A mediator in septic shock. Tidsskrift for den Norske Laegeforening: Tidsskrift for Praktisk Medicin Ny Raekke 108(23): 1790-1792, 1988

Tumor necrosis factor a mediator of endotoxic shock. Journal of Clinical Chemistry and Clinical Biochemistry 25(4): 228-229, 1987

Tumor necrosis factor-alpha. A multifaceted mediator of inflammation. Chest 96(3): 457-459, 1989

Tumor necrosis factor: a plurifunctional mediator of acute inflammation. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology Inc 1(3): 242-247, 1988

Tumor necrosis factor as a mediator of inflammation in influenza A viral pneumonia. Microbial Pathogenesis 19(3): 175-183, 1995

Pharmacological evidence for tumor necrosis factor as a mediator of allergic inflammation in the airways. Journal of Pharmacology and Experimental Therapeutics 278(2): 847-853, 1996

A mediator role for metallothionein in tumor necrosis factor-induced lethal shock. Journal of Experimental Medicine 194(11): 1617-1624, 2001

Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation. Arthritis and Rheumatism 38(1): 105-109, 1995

Experimental cancer cachexia: the role of host-derived cytokines interleukin (IL)-6, IL-12, interferon-gamma, and tumor necrosis factor alpha evaluated in gene knockout, tumor-bearing mice on C57 Bl background and eicosanoid-dependent cachexia. Cancer Research 60(19): 5488-5493, 2000