EurekaMag
+ Translate
+ Most Popular
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
Observations on the Umaria marine bed
10 years of hearing conservation in the Royal Air Force
Chocolate crumb - dairy ingredient for milk chocolate
Effect of daily gelatin ingestion on human scalp hair
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
The composition of pampas-grass (Cortaderia argentea.)
The Accraian Series:
The mechanism of the Liebermann-Burchard reaction of sterols and triterpenes and their esters
Cerebrovascular Doppler ultrasound studies (cv-Doppler)
Toria: PT-303 - first national variety
Hair growth promoting activity of tridax procumbens
Productivity of Pekin x Khaki Campbell ducks
A stable cytosolic expression of VH antibody fragment directed against PVY NIa protein in transgenic potato plant confers partial protection against the virus
Solar treatment of wheat loose smut
Swimmers itch in the Lake of Garda
Bactofugation and the Bactotherm process
The effects of prefrontal lobotomy on aggressive behavior in dogs
Visual rating scales for screening whorl-stage corn for resistance to fall armyworm
Breakdown of seamounts at the trench axis, viewed from gravity anomaly
Kooken; pennsylvania's toughest cave
Recovery of new dinosaur and other fossils from the Early Cretaceous Arundel Clay facies (Potomac Group) of central Maryland, U.S.A
Zubor horny (Bison bonasus) v prirodnych podmienkach Slovensku
The extended Widal test in the diagnosis of fevers due to Salmonella infection
Hair of the american mastodon indicates an adaptation to a semi aquatic habitat

Virus-neutralizing activity, serologic heterogeneity, and retrovirus isolation from homosexual men in the Los Angeles area


Virus-neutralizing activity, serologic heterogeneity, and retrovirus isolation from homosexual men in the Los Angeles area



Virology 150(1): 1-9



ISSN/ISBN: 0042-6822

PMID: 3006329

DOI: 10.1016/0042-6822(86)90260-6

Human retroviruses have been causally associated with the development of the acquired immune deficiency syndrome (AIDS) in groups of individuals at high risk including intravenous drug users, hemophiliacs, and homosexual men. Aside from classic AIDS, homosexual men also develop persistent generalized lymphadenopathy (PGL) which is considered a part of the AIDS-related complex (ARC). We have isolated 70 strains of retroviruses related to human T-lymphotropic viruses type III (HTLV-III) from patients with PGL, AIDS, or ARC. Analyses of sera from these patients indicated a high degree of serologic heterogeneity in the antibody titers and their reactivities toward various HTLV-III viral proteins. In addition, we have detected virus-neutralizing antibodies in approximately 50% of the serum samples tested from patients with PGL or AIDS. This is the first comprehensive virologic and serologic report on more than 100 patients studied at one institution in Los Angeles.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 018205720

Download citation: RISBibTeXText

Related references

Serologic responses to herpes simplex virus in rabbits: complement-requiring neutralizing, conventional neutralizing, and passive hemagglutinating antibodies. Journal of Infectious Diseases 129(6): 623-636, 1974

Five to seven-year serologic follow-up of hepatitis C virus antibody reactive homosexual men. IXTH INTERNATIONAL CONFERENCE ON AIDS and THE IVTH STD WORLD CONGRESS Author IXth International Conference on AIDS in affiliation with the IVth STD World Congress : 349, 1993

Long-term serologic follow-up of hepatitis C virus-seropositive homosexual men. Clinical and Diagnostic Laboratory Immunology 2(2): 219-224, 1995

Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice. Vaccine 31(11): 1540-1547, 2013

Serologic survey for neutralizing antibodies against group B coxsackieviruses in normal population in Delhi area. Indian Journal of Medical Research 76: 656-661, 1982

Serologic activity against retrovirus in patients with Sjögren syndrome. Medicina Clinica 100(4): 121-124, 1993

Isolation of high and low molecular weight components from chicken sera that have Rous sarcoma virus neutralizing activity. Poultry Science 61(8): 1573-1578, 1982

Excessive neutralizing activity against the canine morbilli virus in an area at increased risk for multiple sclerosis. Revista de Medicina Interna Neurologie Psihiatrie Neurochirurgie Dermato-Venerologie. Neurologie Psihiatrie Neurochirurgie 33(3): 199-202, 1988

Human retrovirus infection and immunodeficiencies. Detection and significance of virus-neutralizing antibodies. Antibiotics and ChemoTherapy 38: 159-166, 1987

Human immunodeficiency virus infection in two cohorts of homosexual men: neutralising sera and association of anti-gag antibody with prognosis. Lancet 1(8525): 119-122, 1987

Serologic survey of neutralizing antibodies against group b coxsackieviruses in a normal population in the delhi area india. Indian Journal of Medical Research 76(NOV): 656-661, 1982

Isolation of therapeutic human monoclonal antibodies for varicella-zoster virus and the effect of light chains on the neutralizing activity. Journal of Medical Virology 79(6): 852-862, 2007

Essential role for virus-neutralizing antibodies in sterilizing immunity against Friend retrovirus infection. Proceedings of the National Academy of Sciences of the United States of America 101(33): 12260-12265, 2004

Serum beta 2 microglobulin and interferon in homosexual males relationship to clinical findings and serologic status to the human t lymphotropic virus. AIDS Research 1(6): 423-438, 1984, 1985

Concordance of human immunodeficiency virus detection by polymerase chain reaction and by serologic assays in a Dutch cohort of seronegative homosexual men. Journal of Infectious Diseases 166(3): 620-622, 1992