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Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis


Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis



American Journal of Physiology. Lung Cellular and Molecular Physiology 287(4): L752-L763



ISSN/ISBN: 1040-0605

PMID: 15194563

DOI: 10.1152/ajplung.00026.2004

Regulated expression of lymphoid enhancer factor 1 (Lef-1) plays an obligatory role in the transcriptional control of epithelial bud formation during airway submucosal gland and mammary gland development. However, regions of the Lef-1 promoter required for spatial and temporal regulation during glandular development have yet to be defined.

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Accession: 018211647

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