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Fixation properties of mutant genes with artificial selection

Fixation properties of mutant genes with artificial selection

Genetique Selection Evolution (Versailles): 173: 351-358

Fixation probabilities (u) of mutant genes, which are initially in single copy and have additive effects on a quantitative trait under truncation selection, are computed using Monte-Carlo simulation. A range of gene effects relative to the phenotypic standard deviation, heritabilities and numbers of parents and progeny are studied. The diffusion approximation is found to be an excellent predictor of u. Selection on individual performance, on within family deviation, on family mean and an index of individual and family mean performance are compared. It is found that, particularly for genes of large effect, u is reduced if much weight is given to family mean.

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