EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

In vitro replication of Nosema algerae (Microsporidia), a parasite of anopheline mosquitoes, in human cells above 36 C






Journal of Eukaryotic Microbiology. September-October; 465: 464-468

In vitro replication of Nosema algerae (Microsporidia), a parasite of anopheline mosquitoes, in human cells above 36 C

Microsporidia form a large and ubiquitous group of obligately intracellular parasitic eukaryotes, increasingly recognized as pathogens in humans. Transmission of invertebrate microsporidia to mammals has been considered impossible because temperature seemed to be a limiting factor for development. Nosema algerae, a microsporidian of anopheline mosquitoes, was cultured in human muscle fibroblasts at temperatures of 31degree C and 38degree C. This is the first record of an invertebrate microsporidian developing in human cells at a temperature above 36degree C. The ultrastructure of N. algerae growing in human muscle fibroblasts is similar to that of Brachiola vesicularum, a microsporidian species previously described in the muscle of an AIDS patient.


Accession: 021180306

PMID: 10519213

DOI: 10.1111/j.1550-7408.1999.tb06062.x



Related references

In vitro replication of Nosema algerae , a parasite of anopheline mosquitoes, in human cells above 36degree C. Journal of Eukaryotic Microbiology 46(5): 464-468, 1999

The susceptibility of some pakistan mosquitoes to nosema algerae microsporidia. Pakistan Journal of Zoology 9(1): 19-22, 1977

Host-parasite relationship of Nosema algerae, a parasite of mosquitoes. Indian Journal of Medical Research 70: 620-624, 1979

Susceptibility of nontarget organisms to Nosema algerae (Microsporida: Nosematidae), a parasite of mosquitoes. Journal of Invertebrate Pathology 28(1): 77-85, 1976

Susceptibility of non-target organisms to Nosema algerae Vavra and Undeen, a microsporidian parasite of mosquitoes. Dissertation Abstracts International 36B: 2058, 1975

Attempts at high grade purification and in vitro activation of the spores of Nosema algerae (Microsporidia, Microspora) from Anopheles stephensi (Diptera) under different physiological conditions. Mitteilungen der Deutschen Gesellschaft fur Allgemeine und Angewandte Entomologie 6(4-6): 504-513, 1988

Versuche zur Hochgradigen Reinigung und in Vitro-Aktivierung der Sporen von Nosema algerae (Microsporidia, Microspora) aus Anopheles stephensi (Diptera) unter physiologischen Bedingungen. Mitteilungen der Deutschen Gesellschaft fuer Allgemeine und Angewandte Entomologie, 64-6: 504-513, 1988

Ribosomal RNA of Nosema algerae and phylogenetic relationship to other microsporidia. Parasitology Research 86(1): 18-23, 2000

Nosema algerae Comparative studies on the in vitro culture, ultrastructure, and antigenic profiles of three isolates, two obtained from humans and one from Anopheles mosquitoes. American Journal of Tropical Medicine & Hygiene 61(3 SUPPL ): 493, Sept, 1999

In vivo germination and host specificity of Nosema algerae in mosquitoes. Journal of Invertebrate Pathology 27(3): 343-347, 1976