Isolation, structure, and synthesis of dolastatin C, a new depsipeptide from the sea hare Dolabella auricularia
Sone, H.; Nemoto, T.; Ojika, M.; Yamada, K.
Tetrahedron Letters 34(52): 8445-8448
1993
ISSN/ISBN: 0040-4039 DOI: 10.1016/s0040-4039(00)61355-2
Accession: 021230719
Dolastain C (1), a new depsipeptide exhibiting weak cytotoxicity, has been isolated from the Japanese sea hare Dolabella auricularia. The structure of 1 was elucidated by spectroscopic analysis and chemical degradation. The synthesis of 1 was carried out to confirm the structure unambiguously.
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