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Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis

American Journal of Human Genetics 83(6): 663-674

Osteoporosis, a highly heritable disease, is characterized mainly by low bone-mineral density (BMD), poor bone geometry, and/or osteoporotic fractures (OF). Copy-number variation (CNV) has been shown to be associated with complex human diseases. The contribution of CNV to osteoporosis has not been determined yet.

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Accession: 022710256

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PMID: 18992858

DOI: 10.1016/j.ajhg.2008.10.006

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