Host neutralizing responses and pathogenesis of hepatitis C virus infection
Zeisel, M.B.; Cosset, Fçois-Loïc.; Baumert, T.F.
Hepatology 48(1): 299-307
2008
ISSN/ISBN: 0270-9139
PMID: 18508291
DOI: 10.1002/hep.22307
Accession: 022776025
Biological therapeutic agents (biologicals), such as monoclonal antibodies (mAbs), are increasingly important in the treatment of human disease, and many types of biologicals are in clinical development. During preclinical drug development, cardiovascular safety pharmacology studies are performed to assess cardiac safety in accord with the ICH S7A and S7B regulations that guide these studies.
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Onishi, S.; Ito, K. 1982: Infection and host responses. (2) Immune responses to hepatitis B virus infection and the development of disease characteristics Nihon Naika Gakkai Zasshi. Journal of the Japanese Society of Internal Medicine 71(10): 1358-1361
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Koziel, M.J. 1997: The role of immune responses in the pathogenesis of hepatitis C virus infection Journal of Viral Hepatitis 4(Suppl 2): 31-41
Zhang, D.; Guo, S.; Schrodi, S.J. 2021: Mechanisms of DNA Methylation in Virus-Host Interaction in Hepatitis B Infection: Pathogenesis and Oncogenetic Properties International Journal of Molecular Sciences 22(18)
Par, A.; Paal, M.; Horanyi, M.; Par, G.; Szekeres Bartho, J.; Hegedus, G.; Gasztonyi, B.; Mozsik, G. 1998: Role of viral and host factors in the pathogenesis of hepatitis C virus infection and in the response to interferon treatment Periodicum Biologorum 100(4): 515-519
Par, A.; Paal, M.; Horanyi, M.; Szekeres Bartho, J.; Par, G.; Gasztonyi, B.; Mozsik, G. 1999: A study of viral and host factors in the pathogenesis of hepatitis C virus infection and in the response to interferon treatment Journal of Hepatology 30(Suppl 1): 254
Lee, H.Bahl 1995: Host responses to hepatitis B virus infection in dialysis patients Blood Purification 13(Suppl 1): 19
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