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Insulin secretion from toadfish islet tissue stimulated by pyridine nucleotides

Insulin secretion from toadfish islet tissue stimulated by pyridine nucleotides

Science 162(3850): 283-284

ISSN/ISBN: 0036-8075

PMID: 4386347

DOI: 10.1126/science.162.3850.283

The addition of glucose stimulated release of insulin from the isolated islet tissue of the toadfish incubated in vitro. Reduced nicotinamide-adenine dinucleotide also stimulated insulin release, whereas the oxidized form had no effect. Both oxidized and reduced nicotinamide-adenine dinucleatide phosphate stimulated insulin release, but the reduced form was significantly more effective.

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