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"Unraveling the tail" of how SRPK1 phosphorylates ASF/SF2

"Unraveling the tail" of how SRPK1 phosphorylates ASF/SF2

Molecular Cell 29(5): 535-537

In this issue of Molecular Cell, Ngo et al. (2008) describe the crystal structure of the SRPK1 protein kinase in complex with its substrate, the spliceosome factor ASF/SF2, providing an unprecedented view of multiple targeting mechanisms in action on a single substrate.

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Accession: 024077561

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PMID: 18342599

DOI: 10.1016/j.molcel.2008.02.009

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