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Autonomic nervous system and skin diseases The autonomic nervous system. II: Clinical and therapeutical aspects of autonomic functional disturbance



Autonomic nervous system and skin diseases The autonomic nervous system. II: Clinical and therapeutical aspects of autonomic functional disturbance



Aktuelle Fragen Psychiat Neurol [bibl Psychiat Neurol] 4(130): 98-138



Morphological findings to date, in so far as they have any pathogenetic significance for individual skin diseases, have failed to reveal specific pathological changes in the peripheral autonomic system. This makes it difficult to judge possible pathogenetic connections. In general two types of reaction, often appearing together, may be distinguished: proliferative and regressive changes. Since evaluation depends on quantitative rather than qualitative differences, pathological alterations of the autonomic nervous structures can only be assessed in a given type of skin disease by systematically investigating the various stages and comparing them with the situation in the healthy surrounding tissue. It must be remembered that morphological appearances are only momentary, so that conclusions as to preceding events can merely be hypothetical. It would be expecting too much of morphological considerations to hope for an answer to the question of causation, which is likely to be multiple in the majority of skin diseases of uncertain origin; the autonomic system will if anything be only a link in the chain.

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