Section 25
Chapter 24,245

Biological properties of bile pigments. I. Hemolytic and ag-glutinant power of bilirubin. II. Variations of the hemo-lytic and agglutinant activity of bilirubin when serum or bile salts are added

Clementi, A.; Condorelli, F.

Bollettino della Societa Italiana di Biologia Sperimentale 4: 482-485


ISSN/ISBN: 0037-8771
Accession: 024244585

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Bilirubin exercises a remarkable agglutinant and hemolytic action. The latter is less intense than the former, agglutination very promptly following the addition of bilirubin, whereas hemolysis occurs only after many hours, and not constantly. Agglutination is still present at a dilution 1: 20,000. Oxidation to biliverdin is followed by a marked decrease of agglutinant and hemolytic activity. Ery-throcyte agglutination is delayed when to bilirubin bile salts or blood serum is added. Hemolysis is delayed by addition of blood serum, but is quickened by addition of bile salts, a summation of their hemolytic action presumably taking place.

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