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Blind Gastric And Duodenal Mucosal Biopsies In Patients With Duodenal Ulcer And Those With An Ulcer-Like Syndrome



Blind Gastric And Duodenal Mucosal Biopsies In Patients With Duodenal Ulcer And Those With An Ulcer-Like Syndrome



Southern Medical Journal 57: 79-84



Blind mucosal biopsies from the fundus, distal antrum and duodenum have been obtained from a series of patients with duodenal ulcers and others with an ulcer-like syndrome, and the findings compared to similar biopsies from a series of control patients. The study shows that a very significant antral gastritis is always present in patients with duodenal ulcer; and the findings also suggest, but do not prove, that antral gastritis precedes the development of duodenal ulcer, and that the fully developed syndrome of duodenal ulcer may be simulated by a severe antral gastritis. The current ideas and thoughts concerning the pathogenesis of peptic ulcer disease should be stimulated by these findings.

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Accession: 024253882

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PMID: 14104654


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