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Changes in cartilage and bone of immature female guinea pigs due to undernourishment. The processes of repair following a period of refeeding



Changes in cartilage and bone of immature female guinea pigs due to undernourishment. The processes of repair following a period of refeeding



Arch Path 30(3): 675-688



In growing [female] guinea pigs underfeeding causes atrophy of the cartilage cells and increased sclerosis of the matrix of the growth zones. Cartilage proliferation and ossification continue, but endochondral and periosteal bone formation proceed at a diminished rate, depending on the degree of underfeeding. On refeeding, the sclerosis of the matrix disappears and the cartilage cells reassume their normal appearance. No lines of arrested growth occur.

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Accession: 024300211

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