Comparative Studies on the Antigenic Structure of eight Strains of Listeria Monocytogenes
Archivum Immunologiae et Therapiae Experimentalis 11: 341-363
ISSN/ISBN: 0004-069X PMID: 14059311 Accession: 024363253
Examination of isolated lipid, sugar, and protein fractions by double-diffusion precipitation disclosed differences between serotypes and also between strains belonging to the same serotype. Virulence of the strains for rabbits differed. It may be assumed that the factor responsible for the pathogenicity of these strains resided in the protein fractions. The study of the fractions isolated from strains of L. monocytogenes with the double-diffusion precipitation test revealed greater differences in antigenic structure between the individual strains than were detected in the H and O antigens with the agglutination reaction in Paterson's study. Presumably, the method herein applied allows differentiation not only of surface antigens, but also of antigens within the bacterial cells.