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Congenital Urogenital Anomalies in Rats including Unilateral Renal Agenesia



Congenital Urogenital Anomalies in Rats including Unilateral Renal Agenesia



Journal of Anatomy 70(Pt 4): 566-576



Renal anomalies were associated with abnormalities in the genital tract on the affected side in a stock of rats primarily used for the injection of endocrine substances and in which microphthalmia has occurred. The abnormalities were encountered only on the left side of the body. The blood relationship existing between affected animals strongly suggests that the defect is hereditary. The form taken by the defect is determined by the stage at which the developmental arrest occurred in the growth of the urogenital system of the embryo. Similar abnormalities appear in man.

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Accession: 024383910

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PMID: 17104614


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