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Derivatized mesoporous silica beads for MALDI-TOF MS profiling of human plasma and urine

Derivatized mesoporous silica beads for MALDI-TOF MS profiling of human plasma and urine

Bioconjugate Chemistry 20(5): 913-923

Matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) is a promising tool for large-scale screening of body fluids for the early detection of human diseases. Proteins, peptides, and metabolites present in cells, tissues, or in body fluids constitute the molecular signatures of individuals. The design and generation of material-based platforms for capturing molecular signatures from body fluids has gained increasing interest in recent years.

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Accession: 024454591

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PMID: 19338374

DOI: 10.1021/bc800510f

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