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Determination of tetanus immunity in guinea pigs after inoculation with tetanus antitoxin to which CaCl2 has been added or with tetanus adsorbate vaccine



Determination of tetanus immunity in guinea pigs after inoculation with tetanus antitoxin to which CaCl2 has been added or with tetanus adsorbate vaccine



Lucrarile Stiintifice Inst Seruri Vaccinuri Pasteur Bucuresti 3: 337-345



The stimulating value of Al(OH)3 as an adjuvant of antitoxin is definitely superior to that of CaCl2. The immunity is stronger and appears earlier although the antitoxin amounts to only 50% of the vaccine dose; while when CaCl2 is employed, the antitoxin amounts to almost 100% of the vaccine dose which, in both cases, is the same (2 ml).

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