Effect of saturated and unsaturated fatty acids on the lipid composition in the blood, liver and aorta in experimental atherosclerosis
Babina, M.V.; Evstigneeva, R.P.
Voprosy Pitaniia 23(6): 56-62
Rabbits, which along with cholesterol, were given arachiden preparation containing essential unsaturated fatty acids, demonstrated a less marked rise in the blood triglyceride level, than could be seen in animals receiving no such acids. Saturated fatty acids, particularly palmitine produced the opposite effect. Under the influence of unsaturated fatty acids the liver accumulated less free cholesterol and triglycerides. An addition of unsaturated and saturated fatty acids to the food allowance of rabbits receiving cholesterol affected in different ways the composition of fatty acids cholesterol ethers, phospholipids and triglycerides of the blood serum and the liver. The former contributed to a better correlation between monosaturated, poly-unsaturated and saturated fatty acids in the listed fractions, while the latter made this correlation less favorable. Unsaturated fatty acids acted somewhat inhibitory on the accumulation of lipids in the aorta, whereas saturated ones tended to intensify it.