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Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis


Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis



Journal of Neuroimmunology 206(1-2): 22-27



ISSN/ISBN: 0165-5728

PMID: 19010554

DOI: 10.1016/j.jneuroim.2008.10.006

LFA-1 (CD11a/CD18) is a member of the beta(2)-integrin family of adhesion molecules important in leukocyte trafficking and activation. Although LFA-1 is thought to contribute to the development of experimental autoimmune encephalomyelitis (EAE) primarily through its functions on effector T cells, its importance on other leukocyte populations remains unexplored.

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Accession: 024571036

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