Effects of Plasma on the Absorption of Zinc by Mammalian Erythrocytes

Okunewick, J.P.; Herrick, S.E.; Hennessy, T.G.

Journal of Cellular and Comparative Physiology 63: 333-337


ISSN/ISBN: 0095-9898
PMID: 14187278
DOI: 10.1002/jcp.1030630308
Accession: 024583050

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The effect of plasma on uptake of Zn65 by rat red cells was determined by in vitro investigation. It was found that the amount of zinc which the cells would absorb per unit time was inversely proportional to the amount of plasma present in the external medium, indicating inhibition of Zn65 uptake by red cells in the presence of plasma. Conversely it was found that previously labeled red cells showed a greater loss of Zn65 to a plasma medium than to a saline medium, indicating that the loss of Zn65 from red cells is facilitated by the presence of plasma.