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Experience in mass gamma-globulin prophylaxis of infectious hepatitis in Lithuanian SSR. n. Comparative data on the effectiveness of different doses and methods of gamma-globulin prophylaxis of infectious hepatitis



Experience in mass gamma-globulin prophylaxis of infectious hepatitis in Lithuanian SSR. n. Comparative data on the effectiveness of different doses and methods of gamma-globulin prophylaxis of infectious hepatitis



Zh Mikrobiol Epidemiol Immunobiol 42(1): 61-66



Two wide epidemiological trials were carried out in 1960 (10, 222 schoolchildren) and in 1961 (78,470 schoolchildren) in various districts of the Lithuanian SSR. Half of the schoolchildren served as control. The method of planned gamma-globulin administration during the pre-epidemic season had considerable advantages over its application according to epidemiological indications in the foci of epidemic hepatitis. At the same time the amount of gamma-globulin used for the prevention of 1 instance of epidemic hepatitis in the 1st case did not exceed that administered in the 2nd one. There were no significant differences in the efficacy of 3 and 1.5 ml doses administered during the pre-epidemic season.

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