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Haemolytic streptococcosis of guinea-pigs. III. Skin test of guinea-pigs infected with haemolytic Streptococcus



Haemolytic streptococcosis of guinea-pigs. III. Skin test of guinea-pigs infected with haemolytic Streptococcus



Japanese Jour Vet Sci 20(5): 193-202



Three antigens, broth culture filtrate, Tyrode's extract and heat-killed cells, were tested against spontaneously infected guinea pigs. Both infected and control animals reacted to the broth culture filtrate antigen, while the other antigens appeared more specific. Further, when heat-killed cells were used, reactions were apparently group C specific, and this was corroborated by desensitization testing. This antigen was fractionated and the nucleoprotein fraction found responsible for the specific skin reaction.

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