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Immunochemical studies on some acetylated proteins; acetylated rabbit serum albumin, an antigen in rabbits



Immunochemical studies on some acetylated proteins; acetylated rabbit serum albumin, an antigen in rabbits



Archives of Biochemistry and Biophysics 72(1): 119-126



1.1. The effects of the acetylation reaction on rabbit serum albumin, bovine serum albumin, human serum albumin, and rabbit -globulin as revealed by immunochemical techniques have been investigated.2.2. Acetylated rabbit serum albumin is shown to be antigenic in rabbits.3.3. Acetylated proteins exhibit cross reactions with the antisera produced against other acetylated proteins.4.4. The bearing of these findings on the implication of NH3+ groups of the antibody in the bovine serum albumin-antibovine serum albumin interaction, and on the conditions for the antigenicity of proteins in general, is discussed.

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Accession: 024823486

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PMID: 13471067

DOI: 10.1016/0003-9861(57)90179-0


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