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In embryonic chicken erythrocytes actively transcribed alpha globin genes are not associated with the nuclear matrix



In embryonic chicken erythrocytes actively transcribed alpha globin genes are not associated with the nuclear matrix



Journal of Cellular Biochemistry 106(1): 170-178



The spatial organization of a 250 Kb region of chicken chromosome 14, which includes the alpha globin gene cluster, was studied using in situ hybridization of a corresponding BAC probe with nuclear halos. It was found that in non-erythroid cells (DT40) and cultured erythroid cells of definite lineage (HD3) the genomic region under study was partially (DT40 cells) or fully (HD3 cells) associated with the nuclear matrix.

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Accession: 024831294

Download citation: RISBibTeXText

PMID: 19003974

DOI: 10.1002/jcb.21987


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