In vivo and in vitro studies of the effect of the disodium slat of ethylenediamine tetra-acetate on human dentine and its endodontic implications

Patterson, S.S.

Oral Surgery Oral Medicine and Oral Pathology 16: 83-103


ISSN/ISBN: 0030-4220
PMID: 13941916
DOI: 10.1016/0030-4220(63)90367-0
Accession: 024834497

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The results of a study of ethylenediamine tetraacetate (EDTA) used in endodontic treatment are reported. There was no evidence of pain when used as an irrigant. When sealed in the root canal for a period of 24 hrs, it seems to inhibit growth of bacteria during that period. The EDTA will reduce the Knoop hardness of dentine from 20 to 80 (depending upon area) to a maximum of 7 in a period of 24 hrs. The tissue reaction is very slight to this material when used properly.