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Influence of acid extract of cattle anterior pituitary gland on bone repair in young guinea pigs



Influence of acid extract of cattle anterior pituitary gland on bone repair in young guinea pigs



Proc Soc Exp Biol And Med 33(1): 177-179



Acid extract of cattle anterior pituitary gland has a growth-promoting effect on the callus formation of fractured bones in young guinea pigs. The healing tendency of fractures is accelerated. This is due to a faster transformation of mesenchymal granulation tissue which is converted (1) directly into osteoblasts, osteoid tissue and bony substance, or (2) indirectly into cartilage and afterwards into bone by way of endochondral ossification. Associated with the increase in formative processes there takes place also a more active absorption of the newly formed tissue. There is noted a parallelism between the formation of cartilage and the rapidity of calcification of the callus on the one hand and the rapidity of endochondral ossification in the epiphyseal line on the other hand.

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Accession: 024850470

Download citation: RISBibTeXText

DOI: 10.3181/00379727-33-8296c


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