Section 25
Chapter 24,913

Isolation of a Viral Agent from the Lungs of Sheep affected with Maedi

Sigurdardottir, B.; Thormar, H.

Journal of Infectious Diseases 114: 55-60


ISSN/ISBN: 0022-1899
PMID: 14118049
DOI: 10.1093/infdis/114.1.55
Accession: 024912567

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Virus was isolated from the lungs of 16 sheep affected with a slowly developing, fatal lung disease, known as maedi. The virus was neutralized by serum from maedi cheep. Attempts to isolate the agent from the lungs of 12 sheep from a maedi-free flock failed. The virus is ether sensitive, about 80 m[mu] in diameter. It grows slowly in tissue culture where it produces a cytopathic effect characterized by the formation of multinuclear giant cells. A possible etiological relationship with maedi is discussed.

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