Micro-electrode studies of cerebellar electrical activity in the frog
Joynt, R.J.
Journal of Physiology 144(1): 23-37
1958
ISSN/ISBN: 0022-3751
PMID: 13599106
DOI: 10.1113/jphysiol.1958.sp006083
Accession: 025012508
The electrical activity of the frog's cerebellum was investigated by the use of subsurface microelectrodes and surface Ag-AgCl electrodes. Two types of activity were observed: a low-voltage, fast activity of 150-250/sec.and a spike activity of 8-40/sec. Steady potentials measured through the cerebellum reveal the granular layer to be negative to the molecular layer. The occurrence and frequency of spike discharge are influenced by the intensity and polarity of direct current stimulation. "Seizure-like" electrical activity is accompanied by slow potential changes; negative drifts with facilitation and positive drifts with inhibition of spike discharges were observed.