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Chapter 25,023

Mitotic activity in white rats in a state of drug-induced sleep

Sokolova, L.V.

Biul Eksperim Biol I Med 48(7): 890-894

1959


DOI: 10.1007/bf00788208
Accession: 025022795

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Single administration of hypnotics in the morning or in the evening induced no changes in the mitotic activity of the cornea, skin and crypts of the small intestine. Prolonged continuous drug-induced sleep for a period of 10-11 hours caused a rise of the mitotic activity in the cornea, slightly increased the mitotic activity in the ear epidermis, but left it unchanged in the crypts of the small intestine. The rise of mitotic activity in the corneal epithelium depends on the profoundness of the animal's sleep.

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