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Non-utilization of a-amino-6-ureido-n-caproic acid, piperidine-2-carboxylic acid, and ot-aminoadipic acid for growth in rats on a lysine-deficient diet



Non-utilization of a-amino-6-ureido-n-caproic acid, piperidine-2-carboxylic acid, and ot-aminoadipic acid for growth in rats on a lysine-deficient diet



Jour Biol Chem 182(1): 75-79



L-alpha-Amino-epsilon-ureido-n-caproic acid, DL-piperidine-2-carboxylic acid, and DL-alpha-aminoadipic acid, higher homologs of the amino acids citrulline, proline, and glutamic acid, respectively, were synthesized. The compounds were tested for their ability to support the growth of rats on a lysine-deficient (zein) diet. None of the compounds showed any ability to support growth.

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