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Novobiocin and neonatal hyperbilirubinemia An investigation of the relationship in an epidemic of neonatal hyperbilirubinemia



Novobiocin and neonatal hyperbilirubinemia An investigation of the relationship in an epidemic of neonatal hyperbilirubinemia



American Journal of Disease Children: 447-453



Novobiocin administration to newborn infants resulted in a 3-fold increase in neonatal hyperbilirubinemia. Similar but less intense yellow skin color was noted in newborn rats receiving novobiocin. Chromatography of the azopigments formed after addition of sulfanilic acid to serum of novobiocin-treated patients did not reveal chromatographically different compounds than the azopigments of patients not treated with novobiocin.

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Accession: 025110701

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