Pancreozymin augmented triolein test

Glass, G.B.; Freud, M.; Weinhouse, M.

Acta Gastro-Enterologica Belgica 28(5): 401-407


ISSN/ISBN: 1784-3227
PMID: 5835810
DOI: 10.1007/bf02233424
Accession: 025199680

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The hypothesis tested is that reliability of the triolein test for fat absorption and pancreatic deficiency can be markedly improved by performing the test under conditions of maximal pancreatic and biliary secretion, the latter being induced by Cekiken, a preparation containing cholecystokinin and pancreozymin. Tests on 18 individuals have shown that triolein absorption is dependent upon stimulation of pancreatic and biliary flow and that enhancement of absorption can be obtained in some cases of pancreatic disease. If absorption defects are due to non-pancreatic causes, pancreozymin often further decreases absorption, probably as a consequence of the increased motility which has been observed to occur. These preliminary tests suggest that the modified triolein test can be of great value in differentiating steatorrhea due to pancreatic disease from that due to other causes.

Pancreozymin augmented triolein test