+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Passive sensitization of human skin by sera of guinea pigs anaphylactically sensitized to ovalbumin

Passive sensitization of human skin by sera of guinea pigs anaphylactically sensitized to ovalbumin

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 77(2): 245-247

Sera from some guinea pigs sensitized with ovalbumin produced passive sensitization of human skin, but sera from others similarly treated were inactive in this respect. All of the antisera showing skin-sensitizing activity were from guinea pigs which had survived anaphylactic shock following challenging injns. However, no antisera were obtained from these pigs before the shock dose. Hence, the effect of the challenging injn. on the formation of this type of antibody could not be assessed. The skin-sensitizing activity of the sera bore no relation to their potency in passive sensitization of guinea pigs. This observation suggests that skin-sensitization and anaphylaxis are mediated by different antibodies, the skin-sensitizing antibody being formed by only a fraction of the guinea pigs in response to a type of stimulation which consistently produced anaphylactic antibody.

(PDF emailed within 0-6 h: $19.90)

Accession: 025207264

Download citation: RISBibTeXText

PMID: 14854008

DOI: 10.3181/00379727-77-18738

Related references

Augmentation of the vagally mediated response to 5 hydroxy tryptamine in the anaphylactically de sensitized atria of guinea pigs in vitro. Journal of Pharmacobio Dynamics 1(4): 238-245, 1978

Airway hyperreactivity modulated by immunotherapy with denatured ovalbumin in ovalbumin-sensitized guinea pigs. Journal of the Formosan Medical Association 97(9): 626-632, 1998

Partial purification of a skin reactive factor in sera of de sensitized guinea pigs. Bulletin Of The Institute Of Immunological Science Hokkaido University: 6-33, 1975

The role of non-precipitating antibodies in the passive sensitization of human skin by rabbit anti-ovalbumin. Journal of Experimental Medicine 92(3): 191-200, 1950

111In-labelled leukocyte migration to the lungs of ovalbumin-sensitized guinea-pigs after aerosol challenge with ovalbumin monitored by gamma scintigraphy. International Archives of Allergy and Immunology 118(1): 51-58, 1999

Immunological studies in tuberculosis. 15. Studies on passive transfer of tuberculin sensitivity. 3.Cross skin sensitivity test in guinea pigs injected with peritoneal exudate cells and serum from guinea pigs sensitized with egg albumin. Ann Rept Res Inst Tuberc Kanazawa Univ 15(3): 241-242, 1957

Comparative analysis of passive cutaneous anaphylaxis and long term skin sensitization activities of guinea pig anti sera. Chinese Journal of Microbiology 8(4): 303, 1975

Passive sensitization of human skin by serum of experimentally sensitized animals. Jour Immunol 36(5): 447-458, 1939

Stimulation of early eosinophil progenitors by a heat stable alveolar macrophage product from ovalbumin-sensitized and non-sensitized guinea pigs. Clinical & Experimental Allergy 27(2): 208-217, 1997

Studies on contact skin reactions and normal skin of passively sensitized guinea-pigs. I. A histological study of test lesions in recipients after passive transfer of dinitrochlorobenzene hypersensitivity with lymphoid cells. Acta Soc Med Upsal 68(5/6): 193-214, 1963

Studies on Contact Skin Reactions and Normal Skin of Passively Sensitized Guinea-Pigs. I. a Histological Study of Test Lesions in Recipients After Passive Transfer of Dinitrochlorobenzene (Dncb) Hypersensitivity with Lymphoid Cells. Acta Societatis Medicorum Upsaliensis 68: 193-214, 1963

De sensitization of anaphylactically sensitized animals by feeding antigen. Journal of Allergy & Clinical Immunology 63(3): 138, 1979

Passive sensitization of the skin of the guinea pig with human antibody. International Archives of Allergy and Applied Immunology 5(3-4): 241-245, 1954

Concerning d'Herelle's claim that human sera may be differentiated as to sex by anaphylactic tests on sensitized guinea pigs. Amer Jour Hyg 7(1): 22-26, 1927

The effects of vitamin E in ovalbumin-sensitized guinea pigs. Methods and Findings in Experimental and Clinical Pharmacology 25(1): 27-31, 2003