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Pharmacological studies on Fritillaria imperialis

Pharmacological studies on Fritillaria imperialis

L Indian J Exp Biol 4(3): 157-160

Pharmacological properties of the minor alkaloldal fraction Isolated from the corms of F. rFrltillarial lmperialis are reported. In anesthetized dogs, the alkaloidal fraction shows an appreciable fall in blood pressure due to cardiac depression and peripheral vasodilatation. Hypotensive effect Is also observed in artificial hypertension. On frog's heart the alkaloidal fraction exhibits cardiotonic effect. The alkaloidal fraction also exhibits antifibrillatory activity resembling that of quinidlne and spasmolytic activity similar to that of papaverine.

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Accession: 025227293

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PMID: 5966954

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