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Research on the behaviour of the lungs diffusion capacity under effort in both normal and silicotic subjects

Research on the behaviour of the lungs diffusion capacity under effort in both normal and silicotic subjects

Lavoro Umano 17(9): 397-415

Changes induced by the muscle work on the lung diffusion capacity determined by a CO-method was studied on 5 normal and 15 silicotic subjects. The work has been carried out on the cycloergometer, with work loads corresponding, for each subject, to the maximal aerobic work and the maximal anaerobic work. In the normal subject the DCO [CO diffusion] increases by 92.4%, in comparison with the values at rest, during slight work (maximal aerobic value) and does not increase for heavy works: the increase of the DCO, in comparison with the values at rest, is of 94.1% during the maximal anaerobic work. In silicotic patients the DCO increases less than in normal subjects and continues to augment proportional to the work load. Pathogenetic interpretations of the different behavior in silicotic patients in comparison with normal subjects are discussed.

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