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Separation and identification of the degradation products of purines and nucleic acids on acid hydrolysis by circular paper chromatography



Separation and identification of the degradation products of purines and nucleic acids on acid hydrolysis by circular paper chromatography



Experientia 9(8): 296-297



Circular paper chromatography of adenine, nucleic acids and adenine compounds after acid hydrolysis show a band in addition to the band occupying the position of glycine. This 2d band was identified as 4(5)-amino-5(4)-imidazol carboxamidine and is specific for adenine compounds and nucleic acids. The importance for quantitative analysis of nucleic acids and adenine compounds is discussed.

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Accession: 025438949

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PMID: 13095433

DOI: 10.1007/bf02156020


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