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Separation of human hemoglobins by starch-gel zone electrophoresis

Separation of human hemoglobins by starch-gel zone electrophoresis

Clinica Chimica Acta; International Journal of Clinical Chemistry 6: 136-141

The separation of normal and abnormal human hemoglobins by starch-gel electrophoresis has been described and the relative mobilities of the different components determined. The method of starch-gel electrophoresis has high resolution and was capable of detecting five protein fractions in normal red cell hemolysates. Fetal hemoglobin was readily separable from normal adult hemoglobin; and elevations of the A2 hemoglobin could be demonstrated in some patients with thalassemia minor although quantitative measurements were not made.

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Accession: 025439505

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PMID: 13696887

DOI: 10.1016/0009-8981(61)90047-x

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