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Spread of a large plasmid carrying the cpe gene and the tcp locus amongst Clostridium perfringens isolates from nosocomial outbreaks and sporadic cases of gastroenteritis in a geriatric hospital

Kobayashi, S.; Wada, A.; Shibasaki, S.; Annaka, M.; Higuchi, H.; Adachi, K.; Mori, N.; Ishikawa, T.; Masuda, Y.; Watanabe, H.; Yamamoto, N.; Yamaoka, S.; Inamatsu, T.

Epidemiology and Infection 137(1): 108-113

2008


ISSN/ISBN: 0950-2688
PMID: 18485266
DOI: 10.1017/s0950268808000794
Accession: 025514753

SUMMARYTo investigate two clusters of diarrhoea cases observed in our geriatric hospital wards, the faecal specimens were analysed. Reversed passive latex agglutination assay revealed that 63.2% and 41.7% of the faecal specimens from each cluster were positive for Clostridium perfringens enterotoxin. PCR assay revealed that 71.4% and 68.8% of C. perfringens isolates from each cluster were positive for the enterotoxin gene (cpe).

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