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Sterilization of media for biochemical processes


Sterilization of media for biochemical processes



Advances in Applied Microbiology 2: 313-319



ISSN/ISBN: 0065-2164

PMID: 13752437

DOI: 10.1021/ie50601a047

Summarizing developments occurring in industrial sterilization procedures during the past decade, it can be stated; (1) Heat sterilization is still the method of choice wherever it can be used. (2) Continuous, high-temperature heat sterilization has been successfully adaped to fermentations from previous use in food processing. (3) The contradiction between Z value and activation energy calculations has not been resolved; in fact, it has not even been adequately recognized. Hence, improved flash processing schedules should be possible when data become available from spore destruction studies at higher temperatures. Such studies should also justify one or the other of the calculation methods, provided either is valid at high temperatures. (4) Radiation sterilization may become useful in the beverage alcohol and perhaps in some other fermentations. However, its adaptation to industrial use is contingent upon development of better and cheaper irradiating equipment.

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Accession: 025523242

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