+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Studies of developing cervical neoplasms



Studies of developing cervical neoplasms



Obstetrics and Gynecology 4(4): 411-417



Related cell-behavior studies were undertaken using the tissue-culture method, which makes it possible to study certain functional and structural properties of tumor cells by isolating them in cultures removed from the influence of the host and comparing them with normal cells of similar origin. Growing tissues in vitro often contributes to the differential diagnosis of doubtful tumors. These studies indicate that tissue-culture methods can demonstrate tissue activity and reflect the cytologic grades of abnormal growths. The more anaplastic the cervical tissue cells are, the greater their activity in culture and the shorter the time for epithelial cell migration with more frequent cell division. There is a gradation of tissue activity from the nearocarcinoma (precancer) stage to clinical cancer of the cervix. Cervical tissues derived from patients showing the precancer cell complex exhibit marked cell activity midway between normal and clinical cancer. Cancer in situ behaves in tissue culture similarly to clinical cancer, the difference being that outgrowth is slightly slower. In vitro studies utilizing the tissue-culture method provide a useful method of observing cell behavior and of measuring velocity of growth in human cervical neoplasms.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 025544046

Download citation: RISBibTeXText

PMID: 13203868


Related references

Papillomavirus infection and uterine cervical intraepithelial neoplasms morphological study of cervical intraepithelial neoplasms in two conizations and hysterectomies series 1957 1968 and 1981 1983. Bulletin du Cancer 72(4): 290-297, 1985

Cytogenetic studies in women with cervical uterine neoplasms. Revista del Instituto Nacional de Cancerologia 19: 564-9 Passim, 1966

Studies of an intermediate schiff leukobase associated with the screening of cervical neoplasms. Medical Science Research 17(9): 429-430, 1989

Pathological studies relating to neoplasms of the hypopharynx and the cervical esophagus. Kurume Medical Journal 16(3): 127-133, 1969

Clinical and morphological studies on spontaneous myelocytomatosis in layer-hens associated with other neoplasms. IV. Pathomorphological studies on an unusually high incidence of neoplasms originating of muscle tissue. Bulgarian Journal of Veterinary Medicine 3(2/3): 135-141, 2000

Clinical and morphological studies on spontaneous myelocytomatosis in layer-hens associated with other neoplasms. V. Pathomorphological studies on an unusually high incidence of low-differentiated renal neoplasms (nephroblastomas). Bulgarian Journal of Veterinary Medicine 4(1): 59-66, 2001

Clinical and morphological studies on spontaneous myelocytomatosis in layer-hens associated with other neoplasms. VII. Pathomorphological studies on the simultaneous occurrence of neoplasms of mesenchymal and epithelial origin in different organs and syste. Bulgarian Journal of Veterinary Medicine 4(3): 189-196, 2001

Cervical conization in the diagnosis and treatment of cervical epithelial neoplasms. Minerva Ginecologica 41(6): 261-263, 1989

Anterior cervical plating for the treatment of neoplasms in the cervical vertebrae. Journal of Neurosurgery 90(1 Suppl.): 27-34, 1999

Extracellular signal-regulated protein kinase is activated in cervical intraepithelial neoplasms but inactivated in invasive cervical carcinoma. Pathology International 56(7): 368-374, 2006

The role of cervical transformational zone as an object of human papilloma virus oncogenic effect in cervical intraepithelial neoplasms and invasive cancer development. Arkhiv Patologii 73(6): 33-37, 2012

Long term results of radical cervical lymphadenectomy according to Roux-Berger in the treatment of cervical metastases from oral cavity neoplasms (considerations on 56 cases with more than 5 year follow-up). Il Policlinico. Sezione Chirurgica 74(5): 341-365, 1967

Studies on the pathogenesis of neoplasms by ionizing radiation. II. Neoplasms of endocrine organs. Cancer Research 19: 1181-1187, 1959

Colonic neoplasms; international agreement on the staging of neoplasms and epidemiologic studies. Nihon Rinsho. Japanese Journal of Clinical Medicine 46(2): 356-365, 1988

Drug therapy of endocrine neoplasms. Part I: Thyroid neoplasms, adrenal neoplasms and parathyroid neoplasms. Medizinische Klinik 95(1): 20-25, 2000