+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Studies on certain biological characteristics of M. mallei and M. pseudomallei. II. Virulence and infectivity for animals

Studies on certain biological characteristics of M. mallei and M. pseudomallei. II. Virulence and infectivity for animals

Jour Bact 55(1): 127-135

The various strains of the organisms studied varied greatly in their virulence. The strains of low virulence tended to produce subacute or chronic forms of the diseases, whereas strains of high virulence produced acute fulminating infections. The virulence of one strain was increased by serial passage in hamsters. Hamsters were easily infected by inoculation by the intraperitoneal, subcutaneous, and respiratory routes. Oral inoculation gave irregular results, but some animals became infected after ingestion of small doses. Of the laboratory animals tested, hamsters were found to be the most susceptible. The MLD in hamsters was 15 to 20 organisms of virulent strains. Ferrets were also very susceptible, but guinea pigs were only moderately susceptible and individual animals varied greatly in the degree of susceptibility. Rabbits, mice, rats, and monkeys were least susceptible.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 025555851

Download citation: RISBibTeXText

Related references

Studies on certain biological characteristics of Malleomyces mallei and Malleomyces pseudomallei; virulence and infectivity for animals. Journal of Bacteriology 55(1): 127-135, 1948

Studies on Certain Biological Characteristics of Malleomyces mallei and Malleomyces pseudomallei: I. Morphology, Cultivation, Viability, and Isolation from Contaminated Specimens. Journal of Bacteriology 55(1): 115-126, 1948

Immunologic studies with Malleomyces mallei and Malleomyces pseudomallei I Serological relationships between M mallei and M pseudomallei. Jour Infect Dis: 46-51, 1950

φX216, a P2-like bacteriophage with broad Burkholderia pseudomallei and B. mallei strain infectivity. Bmc Microbiology 12: 289, 2012

Immunologic studies with Malleomyces mallei and Malleomyces pseudomallei. II. Agglutination and complement fixation tests in man and laboratory animals. Jour Infect Dis 86(1): 52-62, 1950

Biological and biochemical studies of the growth of virulence of several septicemic and blood-infective agents. VI. Dehydrogenase activity of Pseudomonas pseudomallei with various virulence. Izvestiia Na Mikrobiologicheskiia Institut 20: 233-238, 1969

Thermostable antigens of Pseudomonas pseudomallei and of Malleomyces mallei and their characteristics in common. Annales de l'Institut Pasteur 112(1): 93, 1967

Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei. Frontiers in Microbiology 2: 151, 2011

PCR-based Methodologies Used to Detect and Differentiate the Burkholderia pseudomallei complex: B. pseudomallei, B. mallei, and B. thailandensis. Current Issues in Molecular Biology 16: 23-54, 2014

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B. pseudomallei, and B. thailandensis. Plos one 11(10): E0164006, 2016

Genomic diversity of Burkholderia pseudomallei clinical isolates: subtractive hybridization reveals a Burkholderia mallei-specific prophage in B. pseudomallei 1026b. Journal of Bacteriology 186(12): 3938-3950, 2004

A Burkholderia pseudomallei macrophage infectivity potentiator-like protein has rapamycin-inhibitable peptidylprolyl isomerase activity and pleiotropic effects on virulence. Infection and Immunity 79(11): 4299-4307, 2011

In Vitro and In Vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei. Clinical and Vaccine Immunology 18(5): 825-834, 2011

Molecular discrimination of Burkholderia pseudomallei and B mallei. Abstracts of the General Meeting of the American Society for Microbiology 102: 261, 2002

Development of Burkholderia mallei and pseudomallei vaccines. Frontiers in Cellular and Infection Microbiology 3: 10, 2013