Studies on fatty acid esters of flavins: XVI. Excretion of riboflavin and riboflavin butyrate into bile of rat after injection of C-labeled riboflavin tetrabutyrate
Yagi, Kunio; Yamada, Masako; Okuda, J.
Vitamins kyoto 37(3): 289-293
Riboflavin-2-14C or its tetrabutyrate was injected to rats and the excretion of riboflavin and its butyrate into bile and feces was studied. In the case of riboflavin-2-14c injection (400ug, total count 2.19 x 105cpm), 41. 25 [mu]g (total count 6. 58 x 103 cpm) were excreted into bile during 3 hr. after the injection and 40. 9 [mu]g (total count 2.07 x 103cpm) into feces during 72 hr. after the injection. In the case of riboflavin tetrabutyrate-2-l4c injection (400 [mu]g in terms of riboflavin, total count 2.19 x 105cpm), only 6. 75 [mu]g (total count 2.14 x 103cpm) of riboflavin and riboflavin tetrabutyrate was excreted into bile during 3 hr. after the injection, 74. 6 [mu]g (total count 4. 68 x 103cpm) into feces during 72 hr. after the injection.