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Chapter 25,596

Studies on urinary excretion of vitamin B12CO60 in pernicious anemia for determining effective dosage of intrinsic factor concentrates

Best, W.R.; White, W.F.; Robbins, K.C.; Landmann, W.A.; Steelman, S.L.

Blood 11(4): 338-351

1956

ISSN/ISBN: 0006-4971
PMID: 13304122
Accession: 025595481
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Urinary excretion of B12CO60 in pernicious anemia patients is increased by low doses of intrinsic factor but with high doses there may be a diminution. There was an incomplete correlation between the hematologic response and the urinary excretion tests.

Related References

Berlin, H.; Berlin, R.; Brante, G.; Sjoberg, S.G. 1958: Studies on intrinsic factor and pernicious anemia. I. Oral uptake of vitamin B12 in pernicious anemia with increasing doses of an intrinsic factor concentrate Scandinavian Journal of Clinical and Laboratory Investigation 10(3): 278-282
Berlin, H.; Berlin, R.; Brante, G.; Sjöberg, S.G. 1958: Studies on Intrinsic Factor and Pernicious Anemia: I. Oral Uptake of Vitamin B 12 In Pernicious Anemia with Increasing Doses of an Intrinsic Factor Concentrate Scandinavian Journal of Clinical and Laboratory Investigation 10(3): 278-282
Berlin, H.; Berlin, R.; Brante, G.; Sjöberg, S.G. 1961: Studies on Intrinsic Factor and Pernicious Anemia: Iii. Intrinsic Factor Activity and B 12 -Binding Power of Electrophoretic Fractions of Intrinsic Factor Concentrates Scandinavian Journal of Clinical and Laboratory Investigation 13(2): 245-248
Sjoberg, S G. 1961: Studies on intrinsic factor and pernicious anemia, II Intrinsic factor activity and B12 -binding power of electrophoretic fractions of intrinsic factor concentrates Scandinavian Jour Clin And Lab Invest: 245-248
Berlin, H.; Berlin, R.; Brante, G.; Sjoberg, S.G. 1961: Studies on intrinsic factor and pernicious anemia. 3. Intrinsic factor activity and Bi2-binding power of electrophoretic fractions of intrinsic factor concentrates Scand. J. Clin. Lab. Invest 13: 245-248
Olsen, H. 1956: Peroral, permanently effective treatment of pernicious anemia with vitamin B12 and intrinsic factor Ugeskrift for Laeger 118(31): 895-897
Heinrich, H.C. 1954: Biochemical principles of diagnosis and therapy of vitamin B12 deficiencies (B12 hypo- and avitaminoses) in man and domestic animals. IV. the resorption distribution and excretion of B12 vitamins after oral therapy of pernicious anemia with crystallized vitamin B12 and intrinsic factor Klinische Wochenschrift 32(35-36): 867-878
Neumann, E.; Honetz, N. 1972: Antibodies against intrinsic factor in oral treatment of pernicious anemia with highly purified hog intrinsic factor-vitamin B 12 complex Blut 24(1): 6-11
Schilling, R.F.; Clatanoff, D.V.; Korst, D.R. 1955: Intrinsic factor studies. III. Further observations utilizing the urinary radioactivity test in subjects with achlorhydria, pernicious anemia, or a total gastrectomy Journal of Laboratory and Clinical Medicine 45(6): 926-934
Schilling, R.F.; Clatanoff, D.V.; Korst, D.R. 1955: Intrinsic factor studies. 3. Further observations utilizing the urinary radioactivity test in subjects with achlorhydria, pernicious anemia, or a total gastrectomy J. Lab. Clin. Med 45: 926-934
Berlin, H.; Berlin, R.; Brante, G.; Andersen, J.G.; Sjoberg, S.G. 1959: Studies on intrinsic factor and pernicious anemia. II. Correlation of intrinsic factor activity to B12 binding power in different hog pylorus preparations Scand Jour Clin And Lab Invest 11(2): 154-161
Gullberg, R.; Kistner, S. 1963: Immunologic Studies of Intrinsic Factor. the Reactions of Experimentally Produced Antisera to Human and Hog Intrinsic Factor and of Sera from Pernicious Anemia Patients Acta Medica Scandinavica 174: 573-581
Wahlstedt, V. 1990: Urinary autoantibodies against intrinsic factor in pernicious anaemia patients British Journal of Haematology 76(3): 420-426
Abels, J.; Woldring, M.G.; Vegter, J.J.; Nieweg, H.O. 1957: Effect of rat intrinsic factor on vitamin B12 absorption in pernicious anemia Science 126(3273): 558
Reisner, E.H.; Weiner, L.; Schittone, M.T.; Henck, E.A. 1955: Oral treatment of pernicious anemia with vitamin B12 without intrinsic factor New England Journal of Medicine 253(12): 502-506