The behavior of alkaline and acid phosphatase in cell cultures from monkey kidneys after infection with ECHO virus serotype 9 and poliovirus hominis type 1

Albrecht, W.; Mittelstrass, H.K.; Sauthoff, R.

ZEITSCHR NATURFORSCH 13b(2): 71-74

1958


Accession: 025687122

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Abstract
The activity of acid phosphatase in the cells declined greatly after infection of Rh-monkey kidney cells, cultured in vitro, with enteric cytopathogenic human origin (ECHO) virus serotype 9 and poliomyelitis virus type 1. It showed a slow rise again after 9 to 12 hours. The activity of the alkaline phosphatase after infection with ECHO virus at first remained unchanged but showed a significant rise after 9 to 12 hours. At the same time, after an initial decrease, an increase in ribonucleic acid in relation to deoxyribonucleic acid was observed. After infection with poliomyelitis virus the activity of the alkaline phosphatase showed a similar although not so marked a behavior. The dependence on time of these shifts in phosphatase activity is related to virus multiplication.