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The determination and clinical correlation of variations in the calcium, inorganic phosphorus, and serum proteins of horse blood


The determination and clinical correlation of variations in the calcium, inorganic phosphorus, and serum proteins of horse blood



American Journal of Veterinary Research 2(3): 227-256



ISSN/ISBN: 0002-9645

410 examinations for Ca, inorganic P, and proteins of the serum obtained from 330 horses were collated according to the effects of sex, age, season of the year, feeding, pregnancy, and pathology. Total Ca ranged from 11.0 to 13.5 mg.%, averaging 12.2 (s.d. 0.5), with principal variations associated with seasonal change and differences in feed. Inorganic P varied grossly from 2 to 8 mg.%, receding gradually with advancing age from 7.1 (s.d. 0.4) in foals less than 3 months old to 3.1 (s.d. 0.6) in horses over 5 years. A seasonal tide was observed in P, with maxima in mid-summer. Total proteins ranged normally from 5-7 mg.%, averaging 6.1 (s.d. 0.3) in [male][male] and non-pregnant [female][female] more than 3 months old. Younger foals showed lower protein levels (5.1) and pregnant mares were higher (6.7). Seasonal change was an important factor in protein variations. A clinical method for the coordination of these data was suggested and demonstrated in a series of diseased subjects. Cases of bone lesions revealed a distinct tendency toward blood deficits in Ca and P, particularly P, with the deficit more pronounced in the more acute cases. Other clinical groups were also studied, including a series of bleeders (spontaneous epistaxis) which failed to manifest deficits in either of these elements.

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Accession: 025722805

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